LI´[ID
Palabras clave:
lipídios, ácidos graxos, carcinogênese mamária experimental, dietasResumen
Os lipídios e ácidos graxos dietários interferem na estrutura e função das membranas biológicas, nos níveis hormonais, no sistema imunológico e no reparo do ácido desoxirribonucléico (DNA). Estes efeitos podem estar relacionados com o desenvolvimento da carcinogênese mamária por mecanismos ainda pouco conhecidos. O aumento do consumo diário de lipídios está fortemente associado com o aumento da incidência e da mortalidade por câncer da mama como demonstrado em várias populações humanas.
Citas
ABRAHAM, S. & HILLYARD, L. A. Effect of dietary 18-carbon fatty acids on growth of transplantable mammary adenocarcinoma in mice. J. Natl. Cancer Inst., Washington, 71: 601-5, 1983.
BURR, G.O. & BURR, M. M. A new deficiency desease produced by the rapid exclusion of fat from the diet. J. Biol. Chem., Batilmore, 82: 345-67, 1929.
BYERS, T. & GRAHAM, S. The epidemiology of diet and cancer. Adv. Cancer Res., New York, 41: 1-69, 1984.
CARROLL, K. K. et al. E. R. Dietary fat and mammary cancer. Can. Med. Assoc. J., Ottawa, 98: 590-4, 1986.
_______ et al. Essential fatty acidsinrelationtomammary carcinogenesis. Prog. Lipid Res., Oxford, 20: 685-9, 1981.
CAVALCANTI, T. C. et al. Mammary mitochondria ATPase of female rats treated by DMBA and two lipid diets. IRCS Med. Sci., Lancaster, 14: 1161-2, 1986.
CHAN, P. C. & COHEN, L. A. Effect of dietary fat, antiestrogen, and antiprolactine on the development of mammary tumors in rats. J. Natl. Cancer Inst., Washington, 52: 25-30, 1974.
________& DAO, T. Enhancement ofmammary carcinogen by a high-fat diet in Fisher, LongEvans, and Sprague-Dawley rats. Cancer Res., Baltimore, 41: 164-7, 1981.
COHEN, L. AÀ. Mechanisms by which dietary fat may stimulate mammary carcinogenesis in experimental animals. Cancer Res., Baltimore, 41: 3808-10, 1981.
HAINES, A. P. Dietary fat intake and the causation of cancer: the epidemiological perspectives. Biochem. Soc. Trans., London, 11:254-6, 1983.
HILLYARD, L. AÀ. & ABRAHAM, S. Effect of dietary polyunsaturated fatty acids on growth of mammary adenocarcinoma in mice and rats. Cancer Res., Baltimore, 39: 4430-7, 1979.
HOPKINS, G. J. et al. Polyunsaturated fatty acids as promoters of mammary carcinogenesis induced in Sprague-Dawley rats by 7,12-dimethylbenz (a) anthracene. J. Natl. Cancer Inst., Washington, 66: 517-22, 1981.
_______ &WEST, C.E. Possible rats of dietary fatin carcinogenesis. Life Sci., Oxford, 19: 1103-16, 1976.
HUBBARD, N. E. & ERICKSON, K. L. Enhancement of metastasis from a transplantable mouse mammary tumor by dietary linoleic acid. Cancer Res., Baltimore, 47: 6171-5, 1987.
KATSOUY ANNI, K. et al. Risk of breast cancer among greek women in relation to nutrient intake. Cancer, Philadelphia, 61: 181-5, 1988.
KOLONEL, L. N. et al. Nutrient intakes in relation to cancer incidences in Hawaii. Br. J. Cancer, London, 44: 332-9, 1981.
MLYAMOTO-TLAVEN, M. et al. Influence of dietary fat on the growth of mammary ducts in BALB/c mice. J. Natl. Cancer Inst., Washington, 67: 179-88, 1981.
NAGASAWA, H. Prolactin: its role in the development of mammary tumors. Med. Hypotheses, Montreal, 5: 1117-21, 1979.
REDDY, K. V. S. & RAY, T. K. Lipid composition of goat mammary gland at different stages of lactation. Indian J. Biochem. Biophys., New Delhi, 18: 182, 1981.
TAHIN, Q. S. Importância fisiológica e patológiéa dos ácidos graxos. Arq. Biol. Tecnol., Curitiba, 28(3): 335-61, 1985.
TANNENBAUM, A. The dependence of tumor formation on the composition of the caloric-restricted diet as well as on the degree of restriction. Cancer Res., Baltimore, 5: 616-25, 1945.
TINSLEY, |. J. et al. Influence of dietary fatty acids on the incidence of mammary tumors in the C3H mouse. Cancer Res., Baltimore, 41: 1460-5, 1981.
WAXLER, S. H. etal. The effect of fat-enriched diet on the incidence of spontaneous mammary tumors in obese mice (40683). Proc. Soc. exp. Biol. Med., 162: 365-8, 1979.
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2023 Tereza Cristina CAVALCANTI, Fernando GUIMARÃES, Quivo S. TAHIN
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
