Latex and fruit allergy in health care workers

Authors

  • Flávia Andréia MARIN Universidade Estadual Paulista
  • Suely Prieto de Barros Almeida PERES Universidade de São Paulo
  • Maria do Carmo VENTURINI Universidade Estadual Paulista
  • Rosane C. Melchiori FRANCISCO Universidade Estadual Paulista
  • Antônio ZULIANI Universidade Estadual Paulista

Keywords:

latex hypersensibility, cross-reactivity, health occupations

Abstract

Introduction
Latex allergy is becoming an increasing risk to exposed individuals, such as the health care workers, and the simultaneous allergy to different types of food, particularly fruits is an aggravating circumstance.

Objective
To estimate the occurrence of hypersensitivity to both fruits and latex among health care workers.

Methods
Fifth-three health care workers, 81.9% of whom women, were studied by means of a specific questionnaire and through puncture cutaneous tests using allergens of latex and fruits (papaya, kiwi, avocado, banana, fig, tomato, nuts) as well as some potential inhalatory allergens.

Results
Of the 53 subjects studied, 15 (28.5%) were allergic to the latex. Hypersensitivity to fruits was diagnosed in 14 (26.4%) individuals, 10 of whom (18.8%) presented a latex positive cutaneous test; papaya (80.0%), kiwi (60.0%) and avocado (50.0%) were the most frequent allergenic fruits.

Conclusion
The present findings indicate a relatively high (18.8%) occurrence of latex-fruit allergy, as already described in the literature. It is important to detect such a condition in health care workers, since they are a potential group at risk.

References

Yagami T, Sato M, Nakamura A, Komiyama T, Kitagawa K, Akasawa A, et al. Plant defense - related enzyme as latex antigens. J Allergy Clin Immunol 1998; 101(3):379-85.

Rueff F, Thomas P, Reissig G, Przybilla B. Natural rubber latex allergy in patients not intensely exposed. Allergy 1998; 53(4) :445-9.

Palczynski C, Walusiak J, Ruta U, Gorski P. Occupational allergy to latex life threatening reaction in health care workers. Report of three

cases. Int J Occup Med Environ Health 1997; 10(3):297-301.

Mace SR, Sussman GL, Liss G, Stark DF, Beezhold D, Thompson R, et al. Latex allergy in operating room nurses. Ann Allergy Asthma Immunol 1998; 80(3):252-56.

Taylor JS, Praditsuwan P. Latex allergy review of 44 cases including outcome and frequent association with allergic hand eczema. Arch Dermatol 1996; 132(3):265-71.

Ebo DG, Stevens WJ, Bris CH, De Clerck LC. Latex- -specific IgE, skin testing, and lymphocyte transformation to latex allergy. J Allergy Clin Immunol 1997; 100(5):618-23.

López S, Di Domênico MSDB, Castro FFM. Alergia ao látex. Rev Bras Alergia Imunopatol 1995; 18(4):126-29.

Latasa M, Dieguez I, Sanz MI, Parra A, Pajaron MJ, Oehling A. Fruit sensitization in patients with allergy to latex. J Invest Allergol Clin Immunol 1995; 5(2):97-102.

Chen Z, Van Kampen V, Raulf-Heimsoth M, Baur X. Allergenic and antigenic determinants of latex allergen Hev b1: peptide mapping of epitopes recognized by human, murine and rabbit antibodies. Clin Expe Allergy 1996; 26(4):406-15.

Yeang HY, Cheong KF, Sunderasan E, Hamzah S, Chew NP, Hamilton RG, et al. The 14.6 Kd rubber elongation factor (He B 1) and 24 Kd (Hev b 3) rubber particle proteins are recognized by IgE from patients with spina bifida and latex allergy. J Allergy Clin Immunol 1996; 98(3):628-29.

Alenius H, Kalkkinen N, Reunala T, Turjanmaa T, Palosuo T. The main IgE-binding epitope of a major latex allergen, prohevein, is present in its N-terminal 43-amino acid fragment, hevein. J Immunol 1996; 156(4):1618-625.

Burrow GH, Vincent KA, Krajbich JI, Aiona MD. Latex allergy in non spina bitida patients: unfamiliar intra-operative anaphylaxis. Aust N Z J Surg 1998; 68(3):183-85.

Cremer K, Hoppe A, Korsch E, Kleine-Diepenbruck U, Blaker F. Natural rubber latex allergy: prevalence and risck factors in patients with spina bifida compared with atopic children and controls. Eur J Pediatr 1998; 157(1):13-6.

Aichane A, Bouayad Z, Outmani A, Afif N, BahlaouiA. Latex allergy in a hospital setting: results of a study in Casablanca. Rev Maladies Resp 1997;

(6):451-55.

Monreal P, Server MT, Torrens I, ESCODA JM. Hypersensitivity to fruits in latex allergic patients. Allergol Immunopathol 1996; 24(1):33-5.

Weiss SJ, Halsey JF. A nurse with anaphylaxis to stone fruits and latex sensitivity: potential diagnostic difficulties to consider. Ann Allergy

Asthma Immunol 1996; 77(6):504-8.

Yagami T, Sato M, Nakamura A, Shono M. One of the rubber latex allergens is a lysozyme. J Allergy Clin Immunol 1995; 96(5):677-86.

Delbourg MF, Guilloux L, Moneret-Vautrin DA, Ville G. Hypersensitivity to banana in latex-allergic patients. Identification of two major banana allergens of 33 and 37 kd. Ann Allergy Asthma Immunol 1996; 76(4):321-26.

Chen Z, Posh A, Cremer R, Raulf-Heimsoth M, Baur X. Identification of hevein (Hev b 6.02) in Hevea latex as major cross-reacting allerg with avocado fruit in patients with latex allergy. J Allergy Clin Immunol 1998; 108(3):476-81.

Sanchez-Monge R. Isolation and characterization of major banana allergens: identification as fruit class I chitinases. Clin Exp Allergy 1999; 29(5): 673-80.

Garcia JCO, Moyano JC, Alvarez M, Bellido J. Latex allergy in fruit-allergic patients. Allergy 1998; 53(5):532-36.

Pepys J. Skin testing. Br Med J 1975; 14:412-15. 23. Osterballe O, Weeke B. A new lancet for skin prick testing. Allergy 1979; 34:209-12.

Siegel S, Castellan Jr, NJ. Nonparametric statistics for the behavioral sciences. 2nd ed. New York: McGraw-Hill; 1988. p.312.

Mourão EMM, Rosário Filho NA. Alergia ao látex. In: Negreiros B, Ungier C. Alergol Clín. São Paulo: Atheneu; 1995. p.389-97.

Geller M, Paiva TCB de Geller P. Alergia ao látex mediada por IgE em centro cirúrgico. Rev Bras Alerg Imunopatol 1997; 20(5):166-8.

Beezhold DH, Sussman GL, Liss GM, Chang NS. Latex allergy can induce clinical reactions to specific foods. Clin Expe Allergy 1996; 26(4):416-22.

Brehler R, Theissen U, Mohr C, Luger T. “Latex-fruit syndrome”: frequency of cross - reacting IgE antibodies. Allergy 1997; 52(4):404-10.

Field EA. Atopy and other risk factors for UK dentists reporting an adverse reaction to latex gloves. Contact Dermatitis 1998; 38(3):132-6.

Allmers H, Huber H, Wirtz C, Kirchner B, Raulf-Heimsoth M, Baur X. Exposure testing with powdered gloves in 60 health care workers with latex allergy. Dtsch Med Wochenschr 1997; 122(43):1308-12.

Safadi GS, Safadi TJ, Terezhalmy JS, Battisto JR, Melton AL. Latex hypersensitivity: its prevalence among dental professionals. J Am Dent Assoc 1996; 127(1):83-8.

Camacho Ibarra VC, Lopez Garcia AI, Galindo Garcia JA, Paz Martinez D, Papaqui Tapia JS. Prevalence of latex hypersensitivity among medical personnel. Rev Alerg Méx; 1997 44(6):150-2.

Moller M, Kayama M, Vieluf D, Paschke A, Steinhart H. Determination and characterization of cross reacting allergens in latex, avocado, banana, and kiwi fruit. Allergy 1998; 53(3):289-96.

Kim KT, Hussain H. Prevalence of food allergy in 137 latex-allergic patients. Allergy Asthma Proc 1999; 20(2):95-7.

Published

2003-12-25

How to Cite

MARIN, F. A., de Barros Almeida PERES, S. P. ., VENTURINI, M. do C., Melchiori FRANCISCO, R. C., & ZULIANI, A. (2003). Latex and fruit allergy in health care workers. Brazilian Journal of Nutrition, 16(4). Retrieved from https://periodicos.puc-campinas.edu.br/nutricao/article/view/9153

Issue

Section

ORIGINAL ARTICLE