Associated factors with dyslipidemia in children 4 to 7 years old
Keywords:
Dyslipidemias, Cross-sectional study, Epidemiologic factors, Child nutritionAbstract
Objective
To evaluate the lipid profile and associated factors with dyslipidemia in children.
Methods
A cross-sectional study that evaluated children 4-7 years old, followed the first months of life in a Program of the Universidade Federal de Viçosa, Minas Gerais. Performed biochemical measurements were total cholesterol, high density lipoprotein, low density lipoprotein and triglycerides. The variables possibly associated with lipid profile were maternal variables, sociodemographic and those associated with the child. Bivariate and multivariate analyses have been done, the latter by multiple logistic regressions.
Results
The sample consisted of 185 children, both genders. It was observed that 46.5% (n=86) showed increased levels of total cholesterol, 9.2% (n=17) of low density lipoprotein and 4.9% (n=9) in triglycerides. With relation to the high density lipoprotein, 35.1% (n=65) had values less than desirable. Demonstrated an independent association with the lipid profile of children the per capita income, maternal education and maternal age (with low density lipoprotein) and overweight, which was associated with a higher prevalence of changes in triglycerides.
Conclusion
High prevalence of dyslipidemia were observed. Sociodemographic conditions and nutritional status demonstrated influence, also in children, the occurrence of dyslipidemia, which are cited as risk factors for cardiovascular disease. Reveals the importance of studying these factors since childhood, performing studies with other age groups to check the prevalence and associated factors to promote the health care of this population group.
References
Talmud PJ, Waterworth DM. In-vivo and in-vitro nutrient-gene interactions. Curr Opinion Lipidol. 2000; 11(4):31-6.
Sposito AC, Caramelli B, Fonseca FAH, Bertolami MC. IV Diretriz Brasileira sobre Dislipidemias e Pre venção da Aterosclerose: Departamento de Ateros clerose da Sociedade Brasileira de Cardiologia. Arq Bras Cardiol. 2007; 88(Supl. 1):2-19.
McMahan CA, Gidding SS, Malcom GT, Tracy RE, Strong JP, McGill HC Jr. Pathobiological determinants of atherosclerosis in youth risk scores are associated with early and advanced atherosclerosis. Pediatrics. 2006; 118(4):1447-55.
Daniels SR, Greer FR. Lipid screening and cardiovascular health in childhood. Pediatrics. 2008; 122(1):198-208. 5. Scherr C, Magalhães CK, Malheiros W. Análise do perfil lipídico em escolares. Arq Bras Cardiol. 2007; 89(2):273-8.
Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH. Prevalence of a metabolic syndrome phenotype in adolescents. Arch Pediatr Adolesc Med. 2003; 157(8):821-7.
Gerber ZRS, Zielinsky P. Fatores de risco de ateros clerose na infância: um estudo epidemiológico. Arq Bras Cardiol. 1997; 69(4):231-6.
Moura EC, Castro CM, Mellin AS, Figueiredo DB. Perfil lipídico em escolares de Campinas, SP, Brasil. Rev Saúde Pública 2000; 34(5):499-505.
Nobre LN, Sammour SNF, Costa Sobrinho OS, Elias FCA, Cavaca SCS, Trindade R, et al. Perfil lipídico e excesso de peso em escolares. Rev Med Minas Gerais. 2008; 18(4):252-9.
Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chemistry. 1972; 18(1):499-502.
Giuliano ICB, Caramelli B, Pellanda L, editores. I Diretriz de Prevenção da Aterosclerose na Infância e na Adolescência. Arq Bras Cardiol. 2005; 85(Supl. 6):3-36.
Rasmussen KM, Yaktine AL, editors. Weight gain during pregnancy: Reexamining the guidelines. Washington (DC): National Academics Press; 2009 [cited 2010 Jun 10]. Available from: http://www. nap.edu/catalog/12584.html
Fisberg RM, Marchioni DM, Slater B. Recomen dações nutricionais. In: Fisberg RM, Slater B, Marchioni DM, Martini LA. Inquéritos alimentares: métodos e bases científicos. São Paulo: Manole; 2005.
Dietpro: soluções em nutrição®. Versão 5i Profissional for Windows. Viçosa: Agromídia Software; 2008.
Institute of Medicine. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids (Macronutrients). Washington (DC): The National Academies Press; 2002.
World Health Organization. Multicentre Growth Reference Study Group. WHO Child Growth Standards: Length/height-for-age, weight-forage, weight-for-length, weight-for-height and body mass index-for-age: Methods and development. Geneva: WHO; 2006.
Onis M, Onyango AW, Borghi E, Siyam A, Nishida C, Siekmann J. Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ. 2007; 85(9):660-7.
Jelliffe DB. Evaluación del estado de nutrición de la comunidad. Geneva: Organización Mundial de Salud; 1968.
Callegari-Jacques SM. Bioestatística: princípios e aplicações. Porto Alegre: Artmed; 2003.
Latorre MRDO. Medidas de risco e regressão logística. In: Massad E, Ortega NRS, Silveira PSP, Menezes RX, organizadores. Métodos quantitativos em medicina. São Paulo: Manole; 2004. p.337-49.
Hosmer DW, Lemeshow S. Applied logistic regression. 2th ed. New York: John Wiley & Sons; 1989.
Gama SR, Carvalho MS, Chaves CRMM. Prevalência em crianças de fatores de risco para as doenças cardiovasculares. Cad Saúde Pública. 2007; 23(9):2239-45.
Romaldini CC, Issler H, Cardoso AL, Diament J, Forti N. Fatores de risco para aterosclerose em crianças e adolescentes com história familiar de doença arterial coronariana prematura. J Pediatr. 2004; 80(2):135-40.
Alcântara Neto OD. Fatores associados à dislipide mia em crianças e adolescentes de escolas públicas de Salvador, Bahia, Brasil [dissertação]. Salvador: Universidade Federal da Bahia; 2010.
Coronelli CLS, Moura EC. Hipercolesterolemia em escolares e seus fatores de risco. Rev Saúde Pública. 2003; 37(1):24-31.
Muratova VN, Islam SS, Demerath EW. Cholesterol screening among children and their parents. Prev Med. 2001; 33(1):1-6.
Geiâ HC, Parhofer KG, Schwandt P. Parameters of childhood obesity and their relationship to cardiovascular risk factors in healthy prepubescent children. Int J Obes. 2001; 25(6):830-7.
Manios Y, Magkos F, Christakis G, Kafatos AG. Changing relationships of obesity and dyslipidemia in Greek children: 1982-2002. Prev Med. 2005; 41(5-6):846-51.
Vasques ACJ. Indicadores do perfil lipídico plasmático relacionado à resistência à insulina. Rev Assoc Med Bras. 2009; 55(3):342-6.
Silva GAP, Balaban G, Motta MEFA. Prevalência de sobrepeso e obesidade em crianças e adolescentes de diferentes condições socioeconômicas. Rev Bras Saúde Mater Infant. 2005; 5(1):53-9.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Taís Cristina Araújo MAGALHÃES, Sarah Aparecida VIEIRA, Silvia Eloiza PRIORE, Andréia Queiroz RIBEIRO, Sylvia do Carmo Castro FRANCESCHINI, Luciana Ferreira da Rocha SANT’ANA
This work is licensed under a Creative Commons Attribution 4.0 International License.
