Continuous or interval aerobic exercise training reduces daily fructose intake in female Wistar rat
Palabras clave:
Appetite, Exercise, Female, FructoseResumen
Objctive
Fructose consumption has increased worldwide. Excessive fructose intake has been a risk factor for the increased metabolic syndrome disorder incidence. This study aimed to investigate the possible influence of two diferente exercise training methods, continuous and interval, on fructose intake.
Methods
Thirty two-months-old female Wistar rats were divided into six groups: sedentary + water ; sedentary + fructose ; continuous training + water ; interval training + water ; continuous training + fructose ; interval training + fructose . Fructose was given in drinking water (10%). Continuous (40 minutes at 40% maximal speed) or interval training (28 minutes, 1 minute at 70%; 3 minutes at 35% maximal speed) sessions were carried out 3 days/week for 8 weeks.
Results
Fructose consumption decreased food intake with a concomitant increase in fluid intake. Continuous and interval training did not modify food intake but progressively reduced fructose ingestion. In the 8th week, interval training + fructose and continuous training + fructose groups drank less fructose solution, 35% and 23%, respectively, than sedentary + fructose group.
Conclusion
The findings indicate that both continuous and interval aerobic exercise training seem to modulate food behavior, possibly by mitigating the craving for sweetness, with interval training being more effective in reducing fructoseintake than continuous exercise.
Citas
Pandita A, Sharma D, Pandita D, Pawar S, Tariq M, Kaul A. Childhood obesity: prevention is better than cure. Dove Press. 2016;9:83-9.
Field AE, Coakley EH, Must A, Spadano JL, Laird N, Dietz WH, et al. Impact of overweight on the risk of developing common chronic diseases during a 10-year period. Arch Intern Med. 2001;161(13):1581-6.
Marriott BP, Cole N, Lee E. National estimates of dietary fructose intake increased from 1977 to 2004 in the United States. J Nutr. 2009;139(6):1228S-1235S.
Lin WT, Kao YH, Sothern MS, Seal DW, Lee CH, Lin HY, et al. The association between sugar-sweetened beverages intake, body mass index, and inflammation in US adults. Int J Public Health. 2020;65(1):45-53.
DiNicolantonio JJ, O’Keefe JH, Lucan SC. Added fructose: a principal driver of type 2 diabetes mellitus and its
consequences. Mayo Clin Proc. 2015;90(3):372-81.
Basaranoglu M, Basaranoglu G, Sabuncu T, Senturk H. Fructose as a key player in the development of fatty liver disease. World J Gastroenterol. 2013;19(8):1166-72.
Schultz A, Neil D, Aguila M, Mandarim-de-Lacerda C. Hepatic adverse effects of fructose consumption independente of overweight/obesity. Int J Mol Med Sci. 2013;14(11):21873-86.
Bray GA, Popkin BM. Dietary sugar and body weight: have we reached a crisis in the epidemic of obesity and diabetes?: Health be damned! pour on the sugar. Diabetes Care. 2014;37(4):950-6.
Weber K, Simon MC, Strassburger K, Markgraf D, Buyken A, Szendroedi J, et al. Habitual Fructose Intake Relates to Insulin Sensitivity and Fatty Liver Index in Recent-Onset Type 2 Diabetes Patients and Individuals without Diabetes. Nutrients. 2018;10(6):774.
Zhang YH, An T, Zhang RC, Zhou Q, Huang Y, Zhang J. Very high fructose intake increases serum LDL-Cholesterol and total cholesterol : a meta-analysis of controlled feeding trials 1–3. J Nutr. 2013;143:1391-8.
Jameel F, Phang M, Wood LG, Garg ML. Acute effects of feeding fructose, glucose and sucrose on blood lipid levels and systemic inflammation. Lipids Health Dis. 2014;13(1):195.
Kelishadi R, Mansourian M, Heidari-Beni M. Association of fructose consumption and components of metabolic syndrome in human studies: a systematic review and meta-analysis. Nutrition. 2014;30(5):503-10.
Perez-Pozo SE, Schold J, Nakagawa T, Sanchez-Lozada LG, Johnson RJ, Lillo JL. Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response. Int J Obes. 2010;34(3):454-61.
Kolderup A, Svihus B. Fructose metabolism and relation to atherosclerosis, Type 2 Diabetes, and Obesity. J Nutr Metab. 2015;2015:823081.
Akram M, Hamid A. Mini review on fructose metabolism. Obes Res Clin Pract. 2013;7(2):e89-94.
Lustig RH. Fructose: metabolic, hedonic, and societal parallels with ethanol. J Am Diet Assoc. 2010;110(9):1307-21.
Lenoir M, Serre F, Cantin L, Ahmed SH. Intense sweetness surpasses cocaine reward. Plos One. 2007;2(8).
Levine AS, Kotz CM, Gosnell BA. Sugars: hedonic aspects, neuroregulation, and energy balance. Am J Clin Nutr. 2003;78(4):3551-62.
Winterdahl M, Noer O, Orlowski D, Schacht AC, Jakobsen S, Alstrup AKO, et al. Sucrose intake lowers μ-opioid and dopamine D2/3 receptor availability in porcine brain. Sci Rep. 2019;9(1):16918.
Volkow ND, Wang GJ, Baler RD. Reward, dopamine and the control of food intake: Implications for obesity. Trends Cogn Sci. 2011;15(1):37-46.
Recio-Roman A, Recio-Menendez M, Roman-Gonzalez MV. Food reward and food choice: an inquiry through the liking and wanting model. Nutrients. 2020;12(3):639.
Lynch WJ, Peterson AB, Sanchez V, Abel J, Smith MA. Exercise as a novel treatment for drug addiction: a neurobiological and stage-dependent hypothesis. Neurosci Biobehav Rev. 2013;37(8):1622-44.
Bardo MT, Compton WM. Does physical activity protect against drug abuse vulnerability? Drug Alcohol Depend. 2015;153:3-13.
Zhou Y, Zhao M, Zhou C, Li R. Sex differences in drug addiction and response to exercise intervention: from human to animal studies. Front Neuroendocrinol. 2016;40:24-41.
Donnelly JE, Blair SN, Jakicic JM, Manore MM, Rankin JW, Smith BK. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc. 2009;41(2):459-71.
Bartlett JD, Close GL, Maclaren DPM, Gregson W, Drust B, Morton JP. High-intensity interval running is perceived to be more enjoyable than moderate-intensity continuous exercise: Implications for exercise adherence. J Sports Sci. 2011;29(6):547-53.
Gallego X, Cox RJ, Funk E, Foster RA, Ehringer MA. Voluntary exercise decreases ethanol preference and consumption in C57BL/6 adolescent mice: sex differences and hippocampal BDNF expression. Physiol Behav. 2015;138:28-36.
Lynch WJ, Robinson AM, Abel J, Smith MA. Exercise as a prevention for substance use disorder: a review of sex differences and neurobiological mechanisms. Curr Addict Rep. 2017;4(4):455-66.
Inam QU, Ikram H, Shireen E, Haleem DJ. Effects of sugar rich diet on brain serotonin, hyperphagia and anxiety in animal model of both genders. Pak J Pharm Sci. 2016;29(3):757-63.
Rebelo MA, Padovan CM, Pereira AC, Moraes C. Moderate-intensity exercise training improves long-term memory in fructose-fed rats. Motriz. 2020;26(4):e10200081.
Oharomari LKLK, Moraes C, Navarro AMAM. Exercise Training but not Curcumin Supplementation Decreases Immune Cell Infiltration in the Pancreatic Islets of a Genetically Susceptible Model of Type 1 Diabetes. Sports Med Open. 2017;3(1):15.
Oharomari LK, Garcia NF, Freitas EC, Jordao Junior AA, Ovidio PP, Maia AR, et al. Exercise training and taurine supplementation reduce oxidative stress and prevent endothelium dysfunction in rats fed a highly palatable diet. Life Sci. 2015;139:91-6.
Malkusz DC, Yenko I, Rotella FM, Banakos T, Olsson K, Dindyal T, et al. Dopamine receptor signaling in the medial orbital frontal cortex and the acquisition and expression of fructose-conditioned flavor preferences in rats. Brain Res. 2015;1596:116-25.
Amador NJ, Rotella FM, Bernal SY, Malkusz D, Cruz JAD, Badalia A, et al. Effect of dopamine D1 and D2 receptor antagonism in the lateral hypothalamus on the expression and acquisition of fructose-conditioned flavor preference
in rats. Brain Res. 2014;1542:70-8.
Kanarek RB, Orthen-Gambill N. Differential effects of sucrose, fructose and glucose on carbohydrate-induced obesity in rats. J Nutr. 1982;112:1546-54.
Darlington TM, McCarthy RD, Cox RJ, Ehringer MA. Mesolimbic transcriptional response to hedonic substitution of voluntary exercise and voluntary ethanol consumption. Behav Brain Res. 2014;259:313-20.
Feeney E, Leacy L, O’Kelly M, Leacy N, Phelan A, Crowley L, et al. Sweet and Umami taste perception differs with habitual exercise in males. Nutrients. 2019;11(1):155.
Jayasinghe S, Kruger R, Walsh D, Cao G, Rivers S, Richter M, et al. Is Sweet taste perception associated with sweet food liking and intake? Nutrients. 2017;9(7):750.
Greenwood BN, Foley TE, Le TV, Strong PV, Loughridge AB, Day HEW, et al. Long-term voluntary wheel running is rewarding and produces plasticity in the mesolimbic reward pathway. Behav Brain Res. 2011;217(2):354-62.
Herrera JJ, Fedynska S, Ghasem PR, Wieman T, Clark PJ, Gray N, et al. Neurochemical and behavioural indices of exercise reward are independent of exercise controllability. Eur J Neurosci. 2016;43(9):1190-202.
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Derechos de autor 2023 Leandro Kansuke OHAROMARI, Mateus Luís MANFRED, Anderson Gregório JOAQUIM, Patricia CHIMIN, Camila DE MORAES
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
