Celiac disease’s relationship with the oral health

Authors

  • Michelle Soares RAUEN Universidade Federal de Santa Catarina
  • Jacqueline Camilli de Vasconcellos BACK Universidade Federal de Santa Catarina
  • Emília Addison Machado MOREIRA Universidade Federal de Santa Catarina

Keywords:

celiac disease, dental enamel hypoplasia, oral manifestations, oral health

Abstract

Celiac Disease is a permanent intolerance to proteins contained in the gluten of some cereals, such as wheat,
rye, barley and oat. The disease appears mainly during the first two years of life, the small bowel being the
main affected organ, with clinical manifestations such as diarrhea, vomiting and weight loss. The diagnosis,
however, is often difficult, due to the large number of atypical manifestations of the disease. In such cases,
numerous and diversified symptoms, such as low stature, anemia, osteoporosis, and dental enamel hypoplasia,
may be concurrent with symptoms of immune diseases associated to the celiac disease (diabetes mellitus,
dermatitis herpetiformis, thyroid diseases, allergy, and recurrent aphtous stomatitis, among others). With
such vast array of symptoms, patients will seek health professionals, who, however, might have trouble
relating the symptoms to the celiac disease. If this illness is not treated properly, chances are that several other
health complications will show up. The objective of this communication is to demonstrate that oral
manifestations are important contributors to the diagnosis of the celiac disease.

References

Walker SJ. Celiac Disease. In: Walker W. Pediatric gastrointestinal disease: Pathophysiology, diagnosis, management. 2nd ed. St. Louis: Mosby; 1996. p.841-61.

Kotze LMS. Distúrbios entéricos da absorção. In: Dani R. Gastroenterologia essencial. Rio de Janeiro: Guanabara Koogan; 1998. p.211-24.

Guevara GP. Enfermedad celíaca. Rev Chil Pediatr. 2002; 73(4):394-7.

Landaburo RV, Pérez FS. Celiaquía: nuevos rostros de una antigua enfermedad. Medicentro 2002; 6(2).

Catassi C, Ratsch IM, Fabiani E, Rossini M, Bordicchia F, Candela F, et al. Coeliac disease in the year 2000: exploring the iceberg. Lancet. 1994; 343(8891):200-3.

Wetiz JCV, Montalva RD, Alarcón TO, Contreras LM. Determinación de anticuerpos anti-transglutaminasa en el diagnóstico de enfermedad celíaca. Rev Méd Chile. 2003; 131(1):25-9.

Romaldini CC, Barbieri D. Anticorpos séricos na doença celíaca. Arq Gastroenterol. 1999; 36(4): 258-64.

Roessler JL, Ríos GM, Alarcón TO, Bergenfreid CO, Moudragón AO, Araya MQ. Enfermedad celíaca en el adolescente y adulto joven. Un desafío para gastroenterólogos de niños y adultos. Rev Méd Chile. 2001; 129(7):743-8.

Sdepanian VL, Morais MB, Neto UF. Doença celíaca: a evolução dos conhecimentos desde sua centenária descrição até os dias atuais. Arq Gastroenterol. 1999; 36(4):244-57.

Morais MB, Sdepanian VL, Neto UF. Doença Celíaca. Nutr Pauta. 2001; 51:30-4.

Sdepanian VL, Scaletsky ICA, Morais MB, Neto UF. Pesquisa de gliadina em medicamentos - informação relevante para a orientação de pacientes com doença celíaca. Arq Gastroenterol. 2001; 38(3):176-82.

Sdepanian VL, Morais MB, Neto UF. Doença celíaca: avaliação da obediência à dieta isenta de glúten e do conhecimento da doença pelos pacientes cadastrados na Associação dos Celíacos do Brasil. Arq Gastroenterol. 2001; 38 (4):232-9.

Santos CHS, Almeida ILB, Gomes MDC, Serafim A, Pereira MM, Muszkat M, et al. Calcificação intracraniana occipital bilateral, epilepsia e doença celíaca. Arq Neuro-Psiquiatr. 2002; 60(3-B): 840-3.

Holmes GKT. Non-malignant complications of coeliac disease. Acta Paediatr. 1996; 85(412):68.

Cataldo F, Marino V, Bottaro G, Greco P, Ventura A. Celiac disease and seletive immunoglobulin a deficiency. J Pediatr. 1997; 131(2):306.

Collin P, Salmi J, Haellstroem O, Reunala T, Pasternack A. Autoimmune thyroid disorders and coeliac disease. Eur J Endocrinol. 1994; 130:7.

Madrid RB, et al. Complicación asociada a la enfermedad celíaca. Med Interna. 2002; 19:81-4.

Ferguson A, Kingstone K. Coeliac disease and malignancies. Acta Paediatr. 1996; 85(412):78.

Sdepanian VL, Morais MB, Neto UF. Doença celíaca: características clínicas e métodos utilizados no diagnóstico de pacientes cadastrados na Associação dos Celíacos do Brasil. J Pediatr. 2001; 77(2):131-8.

Kotze LMS, Utiyama SRR, Nisihara RM, Mocelin V, Carvalho RFA, Zeni MPB, et al. Comparação dos anticorpos anti-reticulina e antiendomísio classe IgA para diagnóstico e controle da dieta na doença celíaca. Arq Gastroenterol 1999; 36(4):177-84.

Lähteenoja H, Toivaner A, Viander M, Maki M, Irjala K, Raiha I, et al. Oral mucosal changes in coeliac patients on a gluten-free diet. Eur J Oral Sci. 1998; 106(5):899-906.

Aine L. Permanent tooth dental enamel defects leading to the diagnosis of coeliac disease. Br Dent J. 1994; 177(7):254-5.

Aine L. Coeliac-type permanent-tooth enamel defects. Ann Med. 1996; 28(1):9-12.

Nikiforuk G, Frase D. The etiology of enamel hypoplasia: a unifying concept. J Pediatr. 1981; 98(6):888-93.

Aguirre JM, Rodríguez R, Oribe D, Vitoria JC. Dental enamel defects in celiac patients. Oral Surg Oral Med Oral Path Oral Radiol Endod. 1997; 84(6):646-50.

Aine L. Dental enamel defects and dental maturity in children and adolescents with coeliac disease. Proc Finn Dent Soc. 1986; 82(3):71.

Aine L, Maki M, Collin P, Keyrilainen O. Dental enamel defects in celiac disease. J Oral Pathol Med. 1990; 19(6):241-5.

Mariani P, Mazzilli MC, Margutti G, Lionetti P, Triglione P, Petronzelli F, et al. Coeliac disease, enamel defects and HLA typing. Acta Paediatr. 1994; 83(12):1272-5.

Smith DMH, Miller J. Gastro-enteritis, coeliac disease and enamel hypoplasia. Br Dent J. 1979; 147:91-5.

Ballinger A, Hughes C, Kumar P, Hutchinson I, Clark M. Dental enamel defects in coeliac disease. Lancet. 1994; 343(22):230-1.

Seow WK. Enamel hypoplasia in the primary dentition: a review. J Dent Child. 1991; 58(6): 441-52.

Pinto GAC. Odontopediatria. 6a.ed. São Paulo: Santos; 1997. Cap. 2.

Maki M, Aine L, Lipsanen V, Koskimies S. Dental enamel defects in first- degree relatives of coeliac disease patients. Lancet. 1991; 337(8744):763-4.

Published

2023-09-21

How to Cite

Soares RAUEN, M. ., de Vasconcellos BACK, J. C. ., & Machado MOREIRA, E. A. (2023). Celiac disease’s relationship with the oral health. Brazilian Journal of Nutrition, 18(2). Retrieved from https://periodicos.puc-campinas.edu.br/nutricao/article/view/9828