Long-term central venous catheter for total parenteral nutrition: Catheter care, permanence period, and incidence of infections

Authors

  • Maria do Rosário Del Lama de UNAMUNO Universidade de São Paulo
  • João José CARNEIRO Universidade de São Paulo
  • Fernando Bahdur CHUEIRE Universidade de São Paulo
  • Júlio Sérgio MARCHINI Universidade de São Paulo
  • Vivian Marques Miguel SUEN Universidade de São Paulo

Keywords:

catheters, parenteral nutrition, sepsis

Abstract

Long-term venous catheters are used for the total parenteral nutrition infusion, which is essential for feeding
short-bowel syndrome patients. However, complications are likely to occur. The incidence of catheter related
infections ranges from 3 to 20% in hospitalized patients. The Divisão de Nutrição Clínica do Hospital das
Clínicas da Faculdade de Medicina de Ribeirão Preto, University of São Paulo, Brazil, has been providing
nutrition support to short-bowel syndrome patients, using totally implantable venous catheters. This is a
retrospective study, which aims to show the Divisão de Nutrição Clínica experience with such catheters, and to
discuss the incidence of infections. We retrospectively evaluated infection complications in 21 catheters
implanted in 16 patients. The permanence-time of the catheters was 768±664.3 days (median: 529 days). The
incidence of infection was 0.029 per patient, per year. These results are comparable to data from developed
countries. Considering that the patients here studied were imunossupressed due to intestinal mal-absorption,
our findings suggest that the catheter care, as provided by our team, contributed to diminish the rate of
infections, and to increase the utilization period of each catheter

References

Brothers T, von Moll LK, Niederhuber JE, Roberts JA, Walker-Andrews S, Ensminger WD. Experience with subcutaneous infusion ports in three hundred patients. Surg Gynecol Obstet. 1988; 166(4): 295-301.

Niederhuber JE, Ensminger WG, Gyves JW, Liepman M, Dora K, Cozzi E. Totally implanted venous and arterial access system to replace external catheters in cancer treatment. Surgery. 1982; 92:706-12.

Vanek VW. The ins and outs of venous access: Part II. Nutr Clin Pract. 2002; 17(3):142-55.

Ryder M. The future of vascular access: Will the benefits be worth the risk? Nutr Clin Pract. 1999; 14:165-9.

Eastridge BJ, Lefor AT. Complications of indwelling venous access devices in cancer patients. J Clin Oncol. 1995; 13(1):233-8.

Groeger JS, Lucas AB, Thaler HT, Friedeander-klar H, Brown AE, Kiehn TE, et al. Infectious morbidity associated with long-term use of venous access devices in patients with cancer. Ann Intern Med. 1993; 119(12):1168-74.

Severien C, Nelson JD. Frequency of infections associated with implanted systems vs cuffed, tunneled Silastic venous catheters in patients with acute leukemia. Am J Dis Child. 1991; 145(12): 1433-8.

Sotir MJ, Lewis C, Bisher EW, Ray SM, Sourcie JM, Blumberg HM. Epidemiology of device-associated infections related to a long-term implantable vascular access device. Infect Control Hosp Epidemiol. 1999; 20(3):187-91.

Sweed MR, Guenter P, Jones S. Nursing implications for the adult patient receiving nutritional support. Medsurg Nurs. 1995; 4(2):99-107.

Vanek VW. The ins and outs of venous access: Part I. Nutr Clin Pract. 2002; 17(2):85-98.

Wurzel CL, Halom K, Feldman JG, Rubin LG. Infection rates of Broviac-Hickman catheters and implantable venous devices. Am J Dis Child. 1988; 142(5):536-40.

Kock HJ, Kranse U, Pietsch M, Rasfeld S, Walz MK. Implantable catheter systems. Experiences with 1000 patients with central venous ports. Dtsch Med Wochenschr. 1996; 121(3):47-51.

Dinc LE. The effectiveness of an educational intervention in changing nursing practice, and preventing catheter-related infection for patients receiving total parenteral nutrition. Int J Nurs Stud. 2000; 37:371-3.

Krzywda EA, Andris DA, Edmiston CE Jr. Catheter infections: diagnosis, etiology, treatment, and prevention. Nutr Clin Pract. 1999; 14:178-90.

Schwank S, Rajacic Z, Zimmerli W, Blaser J. Impact of bacterial biofilm formation on in-vitro and in vivo activities of antibiotics. Antimicrob Agents Chemother. 1998; 42:895-8.

Byers K, et al. Case fatality rate for catheter-related bloodstream infections: A meta-analysis. Proceedings of the 5th annual meeting of the Society for Hospital Epidemiology of America. San Diego, CA, April 2-4, 1995.

Stillman RM, Soliman F, Garcia L, Sawyer PN. Etiology of catheter-associated sepsis. Correlation with trombogenicity. Arch Surg. 1977; 112(12): 1497-9.

Raad II, Hanna HA. Intravascular catheter-related infections: new horizons and recent advances. Arch Intern Med. 2002; 162(8):871-8.

Raad II, Luana M, Khalil SA, Casterton JW, Lam C, Bodey GP. The relationship between the thrombotic and infectious complications of central venous catheters. JAMA. 1994; 271:1014-6.

Timsit JF, Farkas JC, Boyer JM, Martin JB, Misset B, Renaud B, et al. Central vein catheter-related thrombosis in intensive care patients: Incidence, risks factors, and relationship with catheter-related sepsis. Chest. 1998; 114(1):207-13.

Unamuno MRDL, et al. Programa de assistência nutricional a pacientes portadores de síndrome do intestino curto. Anais do 11o Congresso da

Sociedade Brasileira de Nutrição Parenteral e Enteral; 1995, out; Caxambu. Caxambu: SBNC; 1995.

Marchini JS, et al. Três anos de tratamento e seguimento de pacientes portadores de síndrome de má absorção grave, portadores de desnutrição refratária à dietoterapia via oral. Rev Bras Nutr Clín. 1996; 11:27-42.

Marchini JS, et al. Síndrome do Intestino Curto: dificuldades de tratamento, sobrevida e evolução clínico-nutricional de longo prazo. Rev Col Bras Cir. 1995; Supl 2:167.

Unamuno MRDL, et al. Experiencia de cuatro años com el catéter venoso permanente totalmente implantable para nutrición parenteral. Anais do 6o Congresso Latino Americano de Cirurgia, 2o Congresso Chileno de Nutrición Clínica; 1997 ago.

Unamuno MRDL, et al. Estudo microbiológico em cateteres venosos totalmente implantados usados para nutrição parenteral nos pacientes da Unidade Metabólica do HCFMRP. Anais do 12o Congresso da Sociedade Brasileira de Nutrição Parenteral e Enteral; 1997 nov; São Paulo. São Paulo: SBNC; 1997.

Halpin DP, O’Byrne P, McEntee G, Hennessy TP, Stephens RB. Effect of a betadine connection shield on central venous catheter sepsis. Nutrition. 1991; 7(1):33-4.

Sitges-Serra A. Strategies for prevention of catheterrelated bloodstream infections. Support Care Cancer. 1999; 7(6):391-5.

Faubion WC, Wesley JR, Khalidi N, Silva J. Total parenteral nutrition catheter sepsis: Impact of the team approach. JPEN. 1986; 10(6):642-5.

Brasil. Secretaria de Vigilância Sanitária do Ministério da Saúde; Portaria 272 abr 8 1998. Brasília; 1998.

Caressia AC, et al. Síndrome de Intestino Curto (SIC): ingestão alimentar domiciliar de pacientes acompanhados no ambulatório da Unidade Metabólica de Nutrição Clínica do Hospital das Clínicas de Ribeirão Preto. Anais do 3o Congresso

Brasileiro de Clínica Médica; 1995 out; São Paulo. São Paulo: SBCM; 1995.

Marchini JS, et al. Suporte Nutricional de longa duração em pacientes, após retirada de mais de dois metros de intestino delgado. Anais do 21o Congresso Brasileiro de Cirurgia, 11o Congresso

Latino Americano de Cirurgia; 1995 set; São Paulo. São Paulo: SBC; 1995.

Marchini JS. Síndrome do intestino curto: aspectos fisiopatológicos, clínicos e suporte nutricional de longa duração. Rev Med. 1994; 27(3/4):310-9.

Nonino CB. Terapia nutricional em pacientes portadores de síndrome de má absorção grave. Anais do 12o Congresso da Sociedade Brasileira de Nutrição Parenteral e Enteral; 1997 nov; São Paulo. São Paulo: SBNC; 1997.

Unamuno MRDL, et al. Complicação infecciosa relacionada a cateter venoso permanente, em uma paciente recebendo nutrição parenteral. Anais do 7o Congreso Latino Americano de Nutrición Parenteral y Enteral, 2o Conferencia Centroamericana Y del Caribe de Nutrición Clínica; 1999 ago.

Pittet D, Tarara D, Wenzel RP. Nosocomial bloodstream infection in critically ill patients: excess length of stay, extra-costs and attributable mortality. JAMA. 1994; 272:1598-601.

Guédon C, Nouvellon M, Lalaude O, Larebours E. Efficacy of antibiotic-lock technique with teicoplamin in staphylococcus epidermidis catheter-related sepsis during long-term parenteral nutrition. JPEN. 2002; 26(2):109-13.

Brandão MR, et al. Cateter totalmente implantável em pacientes oncológicos. Experiência de 46.076 dias. Rev Bras Nutr Clín. 1997; 12:66-72. 38. Schmidt-Sommerfeld E. Catheter-related complications in 35 children and adolescents with gastrointestinal disease, on home parenteral nutrition. JPEN. 1990; 14(2):148-53.

Mueller BU, Skelton J, Callender DP, Marshall D, Gress J, Longo D, et al. A prospective randomized trial comparing the infectious and non-infectious complications of an externalized catheter versus a subcutaneously implanted device in cancer patients. J Clin Oncol. 1992; 10(12):1943-8.

Young GP, Alexeyeff M, Russel DM, Thomas RJ. Catheter sepsis during parenteral nutrition: The safety of long-term opsite dressings. JPEN. 1988; 12(4):365-70.

Cuntz D, Michaud L, Guimber D, Husson MO, Gottrand F, Turck D. Local antibiotic lock for the treatment of infections related to central catheters in parenteral nutrition in children. JPEN. 2002; 26(2):104-8.

Issam RI, Hend H. Intravascular catheter related infections: new horizons and recent advances. Arch Intern Med. 2002; 162:871-8.

O‘keefe SJD, Burnes JU, Thompson RL. Recurrent sepsis in home parenteral nutrition patients: an analysis of risk factors. JPEN. 1994; 18(3):256-63.

Ma TY, Yoshinaka R, Banaag A, Johnson B, Davis S, Berman SM. Total parenteral nutrition via multilumen catheter does not increase the risk of catheter-related sepsis: a randomized, prospective study. Clin Infec Dis. 1998; 27(3):500-3.

Eyer S, et al. Catheter related sepsis: prospective, randomized study of three methods of long-term catheter maintenance. Crit Care Med. 1990; 18(10):1073-9.

Published

2023-09-21

How to Cite

Del Lama de UNAMUNO, M. do R. ., CARNEIRO, J. J. ., Bahdur CHUEIRE, F. ., MARCHINI, J. S., & Marques Miguel SUEN, V. . (2023). Long-term central venous catheter for total parenteral nutrition: Catheter care, permanence period, and incidence of infections. Brazilian Journal of Nutrition, 18(2). Retrieved from https://periodicos.puc-campinas.edu.br/nutricao/article/view/9827