Association among serum concentration of minerals, anthropometric indices and diarrhea in low-income children in the metropolitan region of Rio de Janeiro, Brazil
Keywords:
anthropometry, micronutrient deficiency, diarrhea, zincAbstract
Objective
The objective of this study was to evaluate the association among blood serum concentrations of iron, zinc, copper, nutritional status and occurrence of diarrhea in children from a low-income community in Duque de Caxias, Rio de Janeiro.
Methods
This is a cross-sectional study that evaluated 104 children aging from 1 to 5 years, selected in the months of April and December 2004, by the project Vila Rosário. The socioeconomic profile of the families and health of the children were assessed, including the occurrence of diarrhea. Nutritional assessment included weight, height/length, weight-for-age and height-for-age indices expressed in Z-scores and classification of the nutritional status based on these indices. Serum concentrations of zinc, iron and copper were determined in a sub-sample (n=59) by synchrotron total reflection x-ray fluorescence.
Results
The children lived in crowded households with unsatisfactory sanitary conditions and were from low-income families. The prevalence of diarrhea in the last moth was 55.7%; 28.4% of the children were underweight and 4.9% were stunted. Iron, zinc and copper deficiencies in the sample were 13.0%, 7.5% and 8.9% respectively. There was no significant association between nutritional indicators and serum concentration of the minerals. Blood serum levels of zinc in children without diarrhea were significantly higher than among those with diarrhea.
Conclusion
Episodes of diarrhea can compromise blood serum levels of zinc in children.
References
World Health Organization. Child Health Research: a Foundation Improving Child Health. Department of Child and Adolescent Health and Development; 2002. Available from: http:www.who.int/en/
Batista Filho M, Rissin A. A transição nutricional no Brasil: tendências regionais e temporais. Cad Saúde Pública. 2003; 19(Suppl 1):181-91.
United Nations Children’s Found. World hunger series 2006: hunger and learning. Vitamin & mineral deficiency: a global progress report. 2003. [cited 2005 Jul 31]. Available from: www.unicef.org/lac/world_hunger_series_2006 _full(1).pdf
Black R. Micronutrient deficiency: an underlying cause of morbity and mortality [Editorial]. Bull World Health Org. 2003; 81(2):79.
Umesh KMD, Abhavna MSC. Adverse effects of poor micronutrient status during childhood and adolescence. Nutr Rev. 2002; 60(5 Suppl 2):84-90.
Mahalanabis D, Bhan, MK. Micronutrients as adjunct therapy of acute illness in children: impact on the episode outcome and policy implications of current findings. Br J Nutr. 2001; 85(Suppl 2):151-8.
Brutta ZA, Black RE, Brown KH, Gardner JM, Gore S, Hidayat AM, et al. Prevetion of diarrhea and pneumonia by zinc supplementation in children in developing countries: pooled analysis of randomized controlled trials. J Pediatr. 1999; 135(6):689-97.
Salgueiro MJ, Zubillaga MB, Lysionek AE. The role of zinc in the growth and development of children. Nutrition. 2002; 18(6):510-9.
Bhandari N, Bahl R, Taneja S. Effect of micronutrient suplementation on linear growth of children. Br J Nutr. 2001; 85(Suppl.2):131-7.
Baqui AH, Zaman K, Persson LA, Arifeen SE, Yunus M, Begum N, et al. Simultaneous weekly supplementation of iron and zinc is associated with lower morbidity due to diarrhea and acute lower respiratory infection in Bangladeshi infants. J Nutr. 2003; 133(12):4150-7.
Singh M. Role of micronutrients for physical growth and mental development. Indian J Pediatrics. 2004; 71(1):59-62.
Walter CF, Black RE. Zinc and the risck for infections disease. Ann Rev Nutr. 2004; 24:255-75.
Baqui AH, Black RE, Arifeen SE, Yunus M, Chakraborty J, Ahmed S, et al. Effect of zinc supplementation started during diarrhoea on morbidity and mortality in Bangladeshi children: community randomised trial. Available from: http://bmj.com/cgi/content/full/325/7372/1059
Krause M, Mahan LK, Escott-Stump S. Alimentos, nutrição e dietoterapia. 9a. ed. São Paulo: Roca; 1998.
Shils ME, Olson JA, Shike M, Ross AC. Tratado de nutrição moderna na saúde e na doença. 9a. ed. São Paulo: Manole; 2003.
Patel AB, Dhande LA, Rawat MS. Economic evaluation of zinc and copper use in treating acute diarrea in children: a randomized controlled trial. Cost Eff Res Alloc. 2003; 29(1):7.
Fisberg M, Naufel CCS, Braga JAP. National prevalence of anaemia in pre school Brazil: 10 Capitals Survey. Ann Nutr Metab. 2001; 45(Suppl.1):450.
Anjos MJ, Costa ACM, Moreira S, Lopes RT, Jesus EFO. Analysis of mineral water from Brazil using total reflection x-ray fluorescence by synchroton radiation. Spectrochimica Acta Part B. 2003; 58(12):2199-204.
Hernández-Carabalho EA, Marcó-Parra LM. Direct analysis of blood serum by total reflection x-ray fluorescence spectrometry and application of an artificial neural network approach for cancer diagnosis. Spectrochimica Acta Part B. 2003; 58:2205-13.
Costa RSS, Carmo MGT, Saunders C, Lopes RT, Jesus EFO, Simabuco SM. Trace elements content of colostrum milk in Brazil. J Food Comp Anal. 2002; 15(1):27-33.
Costa-Neto C. Vila Rosário: o resgate de uma sociedade pela ciencia, pela tecnologia, pelo trabalho e pela compreensão. Rio de Janeiro: Cálamo Produção Editorial; 2002.
Monteiro CA. A dimensão da pobreza, da desnutrição e da fome no Brasil: implicações para políticas públicas. Trabalho apresentado no Seminário Especial Fome e Pobreza pelo Instituto Nacional de Altos Estudos; 2003 [acesso em set 2003]; Rio de Janeiro. Disponível em: http://forumnacional.org.br
Roche AF. Antropometry and ultrasound. In: Roche AF, Heymsfield SB, Lohman TG, editors. Human body composition. Champaign: Humam kinetics; 1996.
World Health Organization. The use and interpretation of antropometry physical status: the use and interpretation of antropometry: report of a WHO expert committee. Geneva; 1995. WHO Technical Report Series 854.
Nakamura NH. Valores laboratoriais e funcionais normais. In: Carvalho WB, Matsumoto T, Hirschheimer MR. Terapia intensiva pediátrica. São Paulo: Atheneu; 1989.
Villalpando S, Garcia-Guerra A, Ramirez-Silva CI, Mejía-Rodrigues F, Chem GM, Shamah-Levy T, et al. Iron, zinc and iodice status in mexican children under 12 years and women 12-49 years of age. A probabilistic national survey. Salud Publica de México. 2003; 45(Suppl 4):520-9.
Milne DB. Copper intake and assessment of copper status. Am J Clin Nutr. 1998; 67(5 Suppl): 1041-5.
Fernandes BS, Jerônimo ML, Leone C. Características familiares e cuidados e condições de saúde das crianças: seu papel no risco de desnutrição protéico-calórica. Pediatria. 1996; 18(2):65-74.
Bhan MJ, Sommerfelt H, Strand T. Micronutrient deficiency in children. Br J Nutr. 2001; 85(Suppl 2):199-203.
Ernan P, Yereli K, Kurt Ö, Balcioglu IC, Onag A. Serological levels of zinc, copper and iron elements among Giardia Lamblia infected children in turkey. Pediatr Int. 2002; 44:286-8.
Hautvast JL, Tolboom JJM, Kafwembe EM, Musonda M, Mwanakasale V, Staveren WAV, et al. Severe linear growth retardation in rural Zambian children: the influence of biological variable. Am J Clin Nutr. 2000; 71(2):550-9.
Penny ME, Marin RM, Duran A, Peerson JM, Lanata CF, Lönnerdal B, et al. Randomized controlled trial of effect of daily supplementation with zinc or multiple micronutrients on the morbidity, growth, and micronutrient sstatus of young Peruvian children. Am J Clin Nutr. 2004; 79(3):457-65.
Monte CMG. Desnutrição: um desafio secular à nutrição infantil. J Pediatria. 2000; 76(Suppl 3): 285-97.
Stephensen CB. Burden of infection on growth failure. J Nutr. 1999; 129(2 Suppl):534-8.
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Copyright (c) 2023 Cássia Viviane Dantas BORGES, Ana Paula Black VEIGA, Gabriela dos Santos BARROSO, Edgar Francisco Oliveira de JESUS, Renata Faria Barbosa SERPA, Silvana MOREIRA, Rosana SALLES-COSTA
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