Alterações provocadas pelo colesterol dietário
Palavras-chave:
aterosclerose, colesterol, dietas, lipoproteínasResumo
Esta revisão mostra a correlação positiva entre os níveis lipídicos plasmáticos e a incidência de doenças coronarianas e explica os mecanismos, pelos quais o colesterol dietário altera os níveis do colesterol plasmático, e também as alterações dos níveis das lipoproteínas plasmáticas, principalmente, da LDL e VLDL consideradas aterogênicas.
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Referências
Anderson, J. T.; Grande, F. & Keys, A. Cholesterol-Iowering diets. J. Am. Diet. Assoe., 62: 133-42, 1973.
Beveridge, J. M. R; Connel, N. F.; Haust, H. A. & Mayer, G. A. The response of man to dietary cholesterol. J. Nutr., 71: 61-5, 1960.
Bierman, E. L. & Glomset, S. A. Disorders of lipid metabolism. In: Williams, R. H., ed. Textbook of endocrinology. 6. NewYork, W. B. Saunders Co., 1981. pp. 876-906.
Brown, M. S.; Kovanen, P. T. & Goldstein, J. L. Regulation of plasma cholesterol by lipoprotein receptors. Science, 212: 625-35, 1981.
Connor, W.; Hodges, R. E. & Blesla, R E. The serum lipids in men receiving high cholesterol and cholesterol free diets. J. Clin. Invest. , 40: 894, 1961.
Etherton-Kris, P. M.; Krummel, D.; Russell, M. E.; Mackey, S.; Brochers, J. & Wood, P. D. The effect of diet on plasma lipids, lipoproteins, and coronary heart disease. National cholesterol education programo J. Am. Diet. Assoe., 98: 1373AOO, 1988.
Flynn, M. A.; Nolph, G. B.; Flynn, T. C.; Kahrs, R. & Krause, G. Effect of dietary egg on human cholesterol and triglycerides. Am. J. Clin. Nutr., 32: 1051-7, 1979.
Ganong,W. F. Fisiologia Médica. 4~ ed., São Paulo, Atheneu Editora São Paulo Uda., 1983, Secção IV, p. 253.
Goldsteins, J. L.& Brown, M. S. Familial hypercholesterolemic: pathogenesis of a receptor disease. John Hopkins Med. J., 143: 8-16, 1978.
Grund, S. M. & Ahrens, E. H. Workshop on the impact of dietary cholesterol on plasma lipoproteins and atherogenesis. Arteriosclerose, 8: 95, 1988.
Keys, A.; Anderson, J. T & Grande, F. Serum cholesterol response to chan~e in the diet. Metab. Clin. Exptl., 14: 747, 1965.
Lasser, N. L.; Roheim, P. S.; Edelstein, D. & Eder, H. A. Serum lipoproteins of normal and cholesterol-fed rats. J. Lipid Res., 14: 1, 1973.
Mabley, R. N.; Innerarity, 1. L.; Bersot, 1. P.; Lipson, A. & Margolis, S. Alterations in human high-density lipoprotein, with on without increased plasma-cholesterol, ipduced by dietshigh in cholesterol. Lancet, 2: 807, 1978.
Mattson, F. H.; Erickson, B. A. & Kliniman, A. M. Effect of dietary cholesterol on serum cholesterol in mano Am. J. Clin. Nutr., 25: 589, 1972.
Mistyr, P.; Miller, N. E.; Laker, M.; Azzard, W. R. & Lewis, B. Individual variation in the effects of dietary cholesterol on plasma lipoprotein and cellular cholesterol homeostasis in mano J. Clin. Invest., 67: 493-502, 1981.
Redgrave, I. G. Formation and metabolism of chylomicrons. Int. Rev. Physiol., 28: 103-30, 1983.
Schaefer, E. J.; Levy, R. 1.; E!.lSt, N. D.; Sant, F. D. & Brewer, H. B. The effects of low cholesterol, high polyunsaturated fat, and low fat diets on plasma lipid and lipoprotein cholestero! levels in normal and hypercholesterolemic subjects. Am. J. Clin. Nutr., 34: 1758-63, 1981.
Shekelle, R. B.; MacMillan, S. A.; Oglesby, P.; Lepper, M. S.; Liu, S. & Raynor, W. D. Diet, serum cholesterol, and death from coronary heart disease. The western eletric study. N. Engl. J. Med., 304: 65-70, 1981.
Shoute-Bronsgeest, D. C.; Hermus, R. J. J.; Thie-Dallinga, M. G. & Hauvast, J. G. A. J. Dependence of the effects of dietary cholesterol and experimental conditions on serum lipids in mano III. The effect on serum cholesterol remotion of eggs from diet of free-living habitually egg-eating people. Am. J. Clin. Nutr., 32: 2193-7,1979.
Small, P. M. & Shipely, G.G. Physical.chemical basis of lipid deposition in atheroscherosis. Am. Ass. Adv. ScL, 185: 222-9,1974.
Srinivasan, S. R.; Radhakrisnamurthy, B.; Smith, C. C.; WOIf, R. H. & Gerenson, G. S.Serum lipid and lipoprotein responses of six
human primate species to dietary changes in cholesterol levels. J. Nutr., 106: 1757, 1976.
Steiner, A.; Howard, E. J. & Akgun, S. Importance of dietary cholesterol in mano J. Am. Med. Assoe., 181: 102-6, 1962.
Trevisan, M.; Krogh, V.; Frevdenheim, J. L.; Blake, A.; Muti, P.; Panico, S.; Farinaro, E.; Mancini, M.; Menotti, A.; Ricci, G. & The Research Group ATS-RF2 of the Italian National ResearchCouncil. Diet and coronary heart disease risk factors, in a population with varied intake. Prev. Med., 19: 231-41,1990.
YOh, S. & Monaco, P. A. Effect of diétary cholesterol and degree of fat unsaturation on plasma lipid levels, lipoprotein compositor and fecal sterois excretion in normal young adult men. Am. J. Clin. Nutr., 42: 399-413, 1985.
