Alterações do metabolismo da glicose na deficiência de magnésio
Palavras-chave:
magnésio, deficiência de magnésio, insulina, glicose, secreção, metabolismoResumo
O magnésio é um cátion essencial o qual age como co-fator para adenosina trifosfatases em inúmeras reações enzimáticas. Vários estudos mostram seu envolvimento na ação e secreção de insulina e os efeitos deste hormônio sobre o metabolismo e transporte do magnésio. Entretanto, os resultados são conflitantes. Sugerem que a deficiência de magnésio está implicada direta ou indiretamente com a resistência à insulina no diabetes mellitus, enquanto outros descrevem uma relação inversa ou, ainda, um aumento da captação de glicose decorrente da falta de magnésio. A interação deste cátion com outros íons, os mecanismos hormonais e neuro-hormonais compensadores e possivelmente a duração da deficiência são alguns dos fatores descritos como responsáveis pelas variações na regulação glicêmica observadas durante a deficiência de magnésio.
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Copyright (c) 2023 Marise Auxiliadora de Barros REIS2, Lício Augusto VELLOSO, Felix Guillermo Reyes REYES
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