Nitrogen balance in mechanically ventilated obese patients

Autores

  • Raquel Stocker PÉRSICO Universidade Federal do Rio Grande do Sul
  • Gabriela Corrêa SOUZA Universidade Federal do Rio Grande do Sul
  • Oellen Stuani FRANZOSI Hospital de Clínicas de Porto Alegre
  • Bibiana de Almeida Rubin ROVATI Hospital de Clínicas de Porto Alegre
  • Zilda Elisabeth de Albuquerque SANTOS Universidade Federal do Rio Grande do Sul

Palavras-chave:

Critical care, Enteral nutrition, Intensive care units, Mechanical ventilation, Nutrition therapy, Obesity

Resumo

Objective
This study aimed to evaluate if the protein intake recommendations for obese critically ill requiring mechanical ventilation are sufficient to promote a positive or neutral nitrogen balance.
Methods
Cross-sectional study that included 25 obese, ≥18 years old, undergoing mechanical ventilation and who were target to receive high-protein enteral nutrition therapy (2.0-2.5g/kg ideal body weight). Clinical, nutritional and biochemical variables were analyzed. Nitrogen balance was performed when patient was receiving full enteral nutrition therapy and was classified: positive when intake was greater than excretion; negative when excretion was greater than intake; neutral when both were equal.
Results
The characteristics of patients evaluated were 64.1±9.4 years old, clinical treatment 88%, body mass index 36.5±5.1kg/m², nitrogen balance 0.3g/day (-5.3 to 4.8g/day), protein intake 2.1g/day (2.0-2.3g/kg) ideal body weight. Of individuals analyzed, 52% showed positive or neutral nitrogen balance with median of 4.23g/day 2.41 to 6.40g/day) in comparison to negative group with median of -5.27g/day (-10.38 to -3.86g/day). Adults had higher ratio of negative nitrogen balance (57.1%) than elderly (44.4%), with protein intake of 2.0 versus 2.1g/day, respectively. No correlation was found between nitrogen balance and variables assessed.
Conclusion
High-protein enteral nutrition therapy contributed to positive or neutral nitrogen balance for approximately half of obese ventilated individuals. With similar protein intake, elderly showed a higher proportion of positive or neutral nitrogen balance. Nitrogen balance can be influenced by various factors, so further studies are required to identify different protein needs in obese critically. 

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Publicado

04-07-2022

Como Citar

Stocker PÉRSICO, R., Corrêa SOUZA, G., Stuani FRANZOSI, O., de Almeida Rubin ROVATI, B., & de Albuquerque SANTOS, Z. E. (2022). Nitrogen balance in mechanically ventilated obese patients. Revista De Nutrição, 34, 1–9. Recuperado de https://periodicos.puc-campinas.edu.br/nutricao/article/view/6116

Edição

v. 34 (2021): Revista de Nutrição

Seção

ARTIGOS ORIGINAIS

Licença

Copyright (c) 2022 Raquel Stocker PÉRSICO, Gabriela Corrêa SOUZA, Oellen Stuani FRANZOSI, Bibiana de Almeida Rubin ROVATI, Zilda Elisabeth de Albuquerque SANTOS

Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.