Rubella: seroprevalence of antibodies among puerperae and newborns during the 2008 vaccination campaign in Botucatu, Brazil

Authors

  • Jaime Olbrich Neto Universidade Estadual Paulista Júlio de Mesquita Filho
  • Sandra Regina Leite Rosa Olbrich Universidade Estadual Paulista Júlio de Mesquita Filho
  • Natalia Leite Rosa Mori Hospital Regional da Associação Beneficente Hospital Sorocabano.
  • Ligia Maria Suppo de Souza Rugolo Universidade Estadual Paulista Júlio de Mesquita Filho
  • Alice Maria KIY Hospital Regional da Associação Beneficente Hospital Sorocabano

DOI:

https://doi.org/10.24220/2318-0897v20n1/2a820

Keywords:

Soroepidemio logic studies, Infant, newborn, Rubella, Vaccines

Abstract

Objective
The present study evaluated the serological status of a representative and randomized sample of puerperae and their children to rubella during a vaccinaüon campaIgn
Methods
This is a cross-sectional study of a representative and randomized sample of
puerperae and newborns during a vaccination campaign that investigated their disease and vaccínation histories. In children, the lgG titer against rubella was repeated at 9 months of age.
Results
A total of 92 puerperae and 51 newborns were evaíuated. The lowest positive status (66.6%), was found among women aged less than 20 years, and the highest (90,40%), among those aged 30 years or older. There was a strong correlation between mothers' and newborns’ lgG. Among women with a history of exanthematous iílness, mean lgG values were significantly higher. Most mothers (62.0%) did not know whether they had been vaccinated. At nine months, none of the children had detectable lgG levels.
Conclusion
It is necessary to evaluate the seroprevalence of women in childbearing age since this group is very vulnerable.

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Author Biographies

Jaime Olbrich Neto, Universidade Estadual Paulista Júlio de Mesquita Filho

1 Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Medicina, Departamento de Pediatria. Campus de Botucatu,
Rubião Júnior, 18618-000, Botucatu, SP, Brasil. Correspondência para/Correspondence to: J OLBRICH NETO. E-mail:
<jolbrich@fmb.unesp.br>.

Sandra Regina Leite Rosa Olbrich, Universidade Estadual Paulista Júlio de Mesquita Filho

2 Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Medicina, Departamento de Enfermagem. Botucatu, SP, Brasil.

Natalia Leite Rosa Mori, Hospital Regional da Associação Beneficente Hospital Sorocabano.

3 Hospital Regional da Associação Beneficente Hospital Sorocabano. Botucatu, SP, Brasil.

Ligia Maria Suppo de Souza Rugolo, Universidade Estadual Paulista Júlio de Mesquita Filho

1 Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Medicina, Departamento de Pediatria. Campus de Botucatu,
Rubião Júnior, 18618-000, Botucatu, SP, Brasil.

Alice Maria KIY, Hospital Regional da Associação Beneficente Hospital Sorocabano

3 Hospital Regional da Associação Beneficente Hospital Sorocabano. Botucatu, SP, Brasil.

References

De Azevedo Neto RS, Silveira AS, Nokes DJ, Yang HM, Passos SD, Cardoso MR, et al. Rubella seroepidemiology in a non-immunized population of São Paulo State, Brazil. Epidemiol Infect. 1994; 113(1):161-73.

Centro de Vigilância Epidemiológica. Norma do programa de imunização. 2ª ed. São Paulo: Secretaria de Estado da Saúde; 2000.

Brasil. Ministério da Saúde. Programa nacional de imunização [Internet]. Brasília: MS; 2008 [acesso 2009

fev. 9]. Disponível em: .

Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Manual técnico-operacional: campanha nacional de vacinação para eliminação da rubéola no Brasil, 2008. Brasília: Ministério da Saúde; 2008.

Inagaki ADM, Oliveira LAR, Oliveira MFB, Santos RCS, Araújo RM, Alves JAB, et al. Soroprevalência de anticorpos para toxoplasmose, rubéola, citomegalovírus, sífilis e HIV em gestantes sergipanas. Rev Soc Bras Med Trop. 2009; 42(5):532-6.

Hood N, Chan MC, Maxwell SM, Familusi JB, Hart CA. Placental transfer of tetanus toxoid antibodies in Nigerian mothers. Ann Trop Paediatr. 1994; 14(3): 179-82.

Centers for Disease Control and Prevention. Revised ACIP recommendation for avoiding pregnancy after receiving a rubella-containing vaccine. MMWR Morb Mortal Wkly Rep. 2001; 50(49):1117-8.

São Paulo. Secretaria de Estado da Saúde. Divisão de Imunização do Centro de Vigilância Epidemiológica “Prof. Alexandre Vranjac”. Campanha nacional de vacinação para eliminação da rubéola no estado de São Paulo. São Paulo: Secretaria de Estado da Saúde; 2008.

Castillo-Solórzano C, Carrasco P, Tambini G, Reef S, Brana M, Quadros CA. New horizons in the controlo frubella and prevention of congenital rubella syndrome in the Américas. J Infect Dis. 2003; 187 (Suppl1):146-52.

Reef SE, Plotkin S, Cordero JF, Katz M, Cooper L, Schwartz B, et al. Preparing for elimination of congenital rubella syndrome (CRS): summary of a workshop on CRS elimination in the United States. Clin Infect Dis. 2000; 31(1):85-95.

Published

2011-04-30

How to Cite

Olbrich Neto, J., Olbrich, S. R. L. R., Mori, N. L. R., Rugolo, L. M. S. de S., & Maria KIY, A. (2011). Rubella: seroprevalence of antibodies among puerperae and newborns during the 2008 vaccination campaign in Botucatu, Brazil. Revista De Ciências Médicas, 20(1/2), 15–21. https://doi.org/10.24220/2318-0897v20n1/2a820

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Artigos Originais